TB-500 is a synthetic peptide fragment corresponding to the active region of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid protein found in high concentrations in platelets, wound fluids, and various tissues. Thymosin Beta-4 functions primarily as an actin-sequestering protein, and TB-500 retains this activity, making it a useful tool in research examining actin dynamics, cellular motility, and the early stages of tissue repair.

Preclinical studies have investigated TB-500’s role in promoting cellular migration of keratinocytes and endothelial cells — processes critical to wound closure and vascular remodeling. Research has also examined its effects on angiogenesis, reporting increases in endothelial cell proliferation and new vessel formation in animal models of ischemia and tissue injury. Studies in musculoskeletal models have explored TB-500’s activity in muscle satellite cell activation and connective tissue repair following injury.

TB-500 is a standard reference compound in research examining actin-binding protein biology, wound healing mechanisms, and angiogenesis. It is frequently studied in combination with BPC-157 in models examining multi-peptide repair synergy. This 5mg lyophilized preparation is suited for research protocols examining Thymosin Beta-4 analog activity in smaller preclinical or in vitro models.

Disclaimer: This product is intended for in vitro research and laboratory use only. It is not intended for human or veterinary use, consumption, or injection. Not approved by the FDA. Not intended to diagnose, treat, cure, or prevent any disease or medical condition. For use by qualified researchers only.