Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is a synthetic peptide analog derived from the adrenocorticotropic hormone (ACTH) 4-10 fragment. Originally developed for neurological research applications, Semax has been studied for its effects on brain-derived neurotrophic factor (BDNF) expression, nerve growth factor (NGF) signaling, and neuroprotective activity in preclinical models. It is among the most researched nootropic peptides in the scientific literature.

Research has examined Semax’s ability to upregulate BDNF and its receptor TrkB in the hippocampus, findings that have positioned it in studies examining neuroplasticity, memory formation, and neuroprotection following ischemic events. Animal studies have investigated Semax’s effects on cognitive task performance, attention, and stress-related behavior. Additional research has explored its influence on enkephalin expression, serotonin receptors, and dopaminergic pathways in the central nervous system.

Semax is a widely referenced compound in neurological research, nootropic peptide pharmacology, and neuroprotection studies. Its well-documented effects on neurotrophic factor expression make it a valuable tool in research examining BDNF-dependent plasticity and peptide-based cognitive research. This 5mg lyophilized preparation is intended for qualified research use.

Disclaimer: This product is intended for in vitro research and laboratory use only. It is not intended for human or veterinary use, consumption, or injection. Not approved by the FDA. Not intended to diagnose, treat, cure, or prevent any disease or medical condition. For use by qualified researchers only.