CJC-1295 (No DAC) — also referred to as Mod GRF 1-29 — is a 29-amino acid synthetic analog of growth hormone-releasing hormone (GHRH). Unlike its DAC-containing counterpart, CJC-1295 without Drug Affinity Complex retains a shorter half-life, mimicking the natural pulsatile release pattern of endogenous GHRH. It is commonly studied in research examining growth hormone secretagogue activity and pituitary somatotroph function.

Preclinical studies have investigated CJC-1295 (No DAC)’s binding affinity to the GHRH receptor and its downstream effects on growth hormone (GH) and insulin-like growth factor-1 (IGF-1) release. The compound’s shorter half-life compared to DAC-modified versions makes it useful in research models where mimicking physiological GH pulse patterns is the primary objective. Studies have examined its pharmacokinetics, receptor binding kinetics, and downstream effects on protein synthesis and lipid metabolism in animal models.

CJC-1295 No DAC is widely referenced in growth hormone axis research, body composition studies, and GHRH analog pharmacology. This 10mg concentration is intended for research protocols requiring larger quantities or extended study durations. Often studied in combination with GHRP peptides such as Ipamorelin to investigate synergistic GH secretagogue effects.

Disclaimer: This product is intended for in vitro research and laboratory use only. It is not intended for human or veterinary use, consumption, or injection. Not approved by the FDA. Not intended to diagnose, treat, cure, or prevent any disease or medical condition. For use by qualified researchers only.